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What Is Multiple Endocrine Neoplasia Syndrome?

Battling cancer begins with being armed with essential information about the disease.

Multiple endocrine neoplasia (MEN) syndromes are genetic disorders in which several endocrine glands develop benign (noncancerous) or malignant (cancerous) tumors, or grow excessively without forming a mass. Tumors or abnormally large glands may occur in more than one gland at a time, often producing excess hormones. These hormones expelled into the bloodstream control many processes of the body, including mood, metabolism, growth and development, sexual function, and reproduction.

Types of Multiple Endocrine Neoplasia We Treat at New Hope

MEN syndromes occur in three patterns:

MEN Type 1

Individuals with multiple endocrine neoplasia type 1 develop either tumors or excessive growth and activity. They occur in two or more glands, including the parathyroid, pituitary, pancreas, thyroid, and adrenal.

MEN Type 2A

Men and women with multiple endocrine neoplasia type 2A develop tumors or excessive growth in two or three glands, including the thyroid, parathyroid, and adrenal.

MEN Type 2B

People diagnosed with multiple endocrine neoplasia type 2B experience neuromas (painful nerve tumor), pheochromocytomas (a rare tumor of adrenal gland tissue), or medullary thyroid cancer.

Multiple Endocrine Neoplasia Symptoms

Warning signs for MEN vary depending on which glands are affected.

Symptoms of multiple endocrine neoplasia type 1 are:

  • Hyperparathyroidism, which presents several symptoms of its own
  • Cushing’s syndrome or a pituitary gland tumor
  • Elevated levels of the hormone gastrin
  • Recurrent ulcers, diarrhea, and abdominal pain
  • Inflammation of the esophagus
  • Issues with sexual function and fertility
  • Headaches and changes in vision
  • Excess discharge of breast milk in women
  • Enlargement of the bones (acromegaly)

Multiple endocrine neoplasia type 2 symptoms are:

  • Tumorous growths around the nerves (neuromas) of the lips and mouth
  • Thickening of the lips and eyelids
  • Small benign tumors on the tongue and lips
  • Irregularities in the bones of the feet and thighs
  • Long limbs and loose joints
  • Arching or deforming of the spine
  • Expansion and irritation of the large intestine

It is important to discuss any physical change or discomfort with your doctor since these symptoms may suggest other health conditions.

Multiple Endocrine Neoplasia Causes

The cause of multiple endocrine neoplasia is a gene mutation handed down in families. If you have any of the MEN syndromes, your child has a 50 percent chance of developing the disease. Unfortunately, nothing can be done to prevent this hereditary disorder. Annual screening for new endocrine tumors, however, can help minimize any associated morbidities and mortalities.

Detection and Diagnosis

Testing for MEN includes conducting a thorough medical and family history, as well as a physical exam to look for signs of excess hormones. A doctor may order further diagnostic exams, such as:

  • Genetic tests, including the screening of family members
  • Checking of hormone levels through blood and urine tests
  • Imaging tests comprising ultrasonography, computed tomography (CT) scan, magnetic resonance imaging (MRI), positron emission tomography (PET), nuclear medicine scan, and endoscopic ultrasound

Choose New Hope for Multiple Endocrine Neoplasia Alternative Treatments

Treatment for multiple endocrine neoplasia (MEN) is most successful when performed by specialists with a great deal of knowledge and experience in handling the disease. The medical team at New Hope Unlimited performs many therapies for cancer each year, using the least-invasive and most-effective techniques. Are you eager to be one step closer to beating MEN syndrome? Click Here for more information.

Our Promise

  • Advanced Cancer Treatments
  • Top-Rated Physicians
  • Personal Care
  • Patient Satisfaction

Our Top-of-the-Line Medical Facilities

At New Hope Unlimited, we pride ourselves in providing superior comfort, cleanliness, and cancer care at our 8,000 square foot medical treatment center in San Luis Rio Colorado, Mexico. We worked with renowned architects and contractors to create the ideal space for recovery, which includes state-of-the-art lounge areas and spacious private in-rooms that assure the comfort of our patients and their loved ones.

To make our patients feel right at home, each private ward is equipped with high-definition U.S. television, quality bedding, and high-speed internet connection. And with proper nutrition playing a vital role in cancer recovery, New Hope Unlimited also fulfills the dietary needs of each patient using fresh, organic produce to prepare breakfasts, lunches, snacks, and dinners.

Comfort and cleanliness are also strictly implemented in our medical treatment rooms, which are equipped with the latest medical supplies and technology to provide the highest standard of care and treatment. Our medical center also has an in-house Hyperbaric Chamber, a well-established therapy for decompression sickness, exclusively available for our patients’ use.

Further, New Hope Unlimited has maintained its exceptional partnership with Hospital Migoo, a medical group comprised of certified physicians and specialists committed to our patients’ care and well-being.


1. What specific treatments does New Hope offer?

Click here to learn about our combination of conventional, alternative, and holistic therapies for multiple endocrine neoplasia syndromes.

2. Will insurance cover alternative treatments for multiple endocrine neoplasia?

Because alternative treatments and holistic protocols still represent a non-conventional area of medicine, most insurance providers typically do not cover them.

3. How common is multiple endocrine neoplasia?

According to the U.S. National Library of Medicine, MEN1 affects about 1 in 30,000 people, while MEN2 affects about 1 in 35,000 people.


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